PACE™ Platform
Parallel | Automated | Chiral | Engine
The PACE™ platform is designed to develop potential small molecule drug candidates by utilizing novel, chiral, diverse chemical libraries for hit identification, with a design-driven intelligence that facilitates efficient hit follow-up, and further enhanced by a co-located automation laboratory.
Hit Identification Hits identified from LCC’s 3D-rich, poised fragment library.
Hit Identification Hits identified from LCC’s 3D-rich, poised fragment library.
Lead Optimisation Proprietary ultra-large virtual chemical library mined to identify innovative lead and drug-like sp3-rich compounds related to the hits
Lead Optimisation Proprietary ultra-large virtual chemical library mined to identify innovative lead and drug-like sp3-rich compounds related to the hits
Selection Target compounds prioritised and selected using computational expertise
Selection Target compounds prioritised and selected using computational expertise
Synthesis Automated parallel synthesis laboratory synthesises target follow-up compounds, with proven chemical tractability enabled by synthesis-led design
Synthesis Automated parallel synthesis laboratory synthesises target follow-up compounds, with proven chemical tractability enabled by synthesis-led design
Optimisation Optimisation cycle repeated to develop potential drug candidates.
Optimisation Optimisation cycle repeated to develop potential drug candidates.
The platform is proven across a range of therapeutic areas to develop small molecule lead candidate assets.